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Updated: Mar 16 2024

Chondrosarcoma

Images
  • summary
  • Epidemiology
  • Etiology
  • Chondrosarcoma subtypes
  • Presentation
  • Imaging
  • Histology
  • Differential
  • Treatment
    • Nonoperative
      • chemotherapy & radiation
        • indications
          • not indicated
          • chondrosarcomas are resistant to chemotherapy and radiation
    • Operative
      • intra-lesional curettage
        • indications
          • Grade 1 lesions in the extremities (minimal rate of metastasis)
          • treatment of grade 1 lesions located in the pelvis or axial skeleton is controversial (higher rate of local recurrence and metastasis)
            • most authors recommend wide excision of all chondrosarcomas (even grade 1) if located in the pelvis
        • technique
          • curettage, high-speed burring, and adjuvant treatment with subsequent packing of the defect, with internal fixation as needed
            • common adjuvants include cryotherapy, liquid nitrogen, argon beam, phenol, ethanol, and hydrogen peroxide
      • wide surgical excision combined with multi-agent chemotherapy
        • indications
          • mesenchymal chondrosarcoma
            • may also respond to radiation
          • possible role for chemotherapy in dedifferentiated chondrosarcoma
  • Complications
  • Prognosis
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Question
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In scope icon L 3
QID 219537 (Type "219537" in App Search)
A 37-year-old male with a past medical history of multiple hereditary exostosis presents to the clinic by referral from your colleague for evaluation of a left shoulder mass. Previous imaging is reviewed, as shown in Figure 1. MRI reveals cortical destruction with a soft tissue mass scattered with intralesional calcifications. He undergoes a biopsy and is subsequently treated with wide resection with endoprosthetic reconstruction. Which of the following histological slides would most likely necessitate the patient's treatment as mentioned above?
  • A
  • B
  • C
  • D
  • E
  • F

Figure B

17%

151/881

Figure C

60%

530/881

Figure D

8%

72/881

Figure E

7%

64/881

Figure F

6%

54/881

  • A
  • B
  • C
  • D
  • E
  • F

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Pathology | Chondrosarcoma
  • Pathology
  • - Chondrosarcoma
15:41 min
12/13/2019
1569 plays
4.8
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(12)
Question Session⎪Chondrosarcoma
  • Pathology
  • - Chondrosarcoma
8:58 min
11/6/2019
108 plays
5.0
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(1)
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