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Review Question - QID 934

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QID 934 (Type "934" in App Search)
A 65-year-old man undergoes a biopsy from his pelvis for a suspicious lesion. The biopsy is shown in Figures A and B. What is the preferred treatment for this condition?
  • A
  • B

Observation

3%

86/2669

Wide excision

69%

1831/2669

Wide excision plus chemotherapy

22%

593/2669

Radiation therapy

5%

130/2669

Cyrotherapy

0%

12/2669

  • A
  • B

Select Answer to see Preferred Response

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The pathological lesion seen in Figure A is that of chondrosarcoma. Unfortunately chondrosarcomas, the second most common primary malignant bone tumor (osteosarcoma being number one) are not chemosensitive or radiosensitive. Patients with this type of tumor who wish to have a chance of cure need to have wide excision of the lesion if possible. No increase in survival rates has been shown with any additional treatment beyond wide local excision.

Donati et al reviewed 124 cases of conventional chondrosarcoma and noted that high-grade tumors require aggressive surgical excision while grade 1 peripheral chondrosarcomas may be treated with contaminated margins in order to reduce morbidity. Low grade tumors with contaminated margins had no difference in survival.

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