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Review Question - QID 2854

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QID 2854 (Type "2854" in App Search)
What is the preferred definitive treatment for biopsy proven grade-2 chondrosarcoma of the distal femur without evidence of metastases?

Curettage

1%

38/3583

Marginal excision

2%

69/3583

Wide excision

86%

3074/3583

Chemotherapy then wide excision

10%

355/3583

Hip disarticulation amputation

1%

28/3583

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The treatment of choice for chondrosarcoma is wide excision, which has better survival than marginal resection or intralesional resection. The rate of recurrence is variable with grade-3 or dedifferentiated tumors having the worst prognosis.

Lee et al. describe outcomes based on resection type and tumor stage and grade. Adjuvant radiation and chemotherapy are generally only used in patients with mesenchymal or dedifferentiated chondrosarcoma or in grade-3 pelvic chondrosarcomas where complete resection is technically difficult and these adjuvant treatments are intended to reduce local recurrence.

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