Review Question - QID 864

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Chondrosarcoma Treatment Operative QID: 864 (OBQ07.203)

QID 864 (Type "864" in App Search)

A 72-year-old male presents with increasing thigh pain. Radiographs and high power biopsy are shown in Figures A and B. Staging studies demonstrate no further sites of disease. What is the next step in treatment?

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Neoadjuvant chemotherapy

229/2823

Neoadjuvant radiation therapy

192/2823

Marginal excision

68/2823

Wide surgical excision and reconstruction

81%

2274/2823

Palliative care

40/2823

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The history, radiograph, and biopsy are consistent with a high grade chondrosarcoma of the proximal thigh.

As described in the review by Marco et al, cartilage tumors are resistant to chemotherapy and radiotherapy and as such the best treatment is wide surgical excision and reconstruction.

Lee et al review one institutions experience with a chondrosarcoma specifically examining the predictors of outcome. They found that adjuvant therapy did not affect overall outcome.