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Review Question - QID 3076

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QID 3076 (Type "3076" in App Search)
A 70-year-old woman falls and presents with pelvic pain. Physical exam shows she is able to walk without difficulty. Radiographs of the pelvis and hip are shown in Figure A, B, and C. A biopsy of the lesion in the proximal femur is shown in Figure D. What is the next best step in management of the femoral lesion?
  • A
  • B
  • C
  • D

Resection and internal fixation

13%

457/3387

Chemotherapy followed by wide resection

5%

160/3387

Observation

79%

2688/3387

Radiation therapy

2%

59/3387

Palliative care

0%

8/3387

  • A
  • B
  • C
  • D

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The lesion is an enchondroma of the proximal femur found incidentally after a fall while sustaining a pubic ramus fracture. Enchondromas are the 2nd most common type of benign cartilage lesions (following osteochondromas) and occur most frequently in patients 20-60 years of age, males and females are affected equally. Most enchondromas are found in the metaphyseal or metadiaphyseal portion of bone. Common sites include bones of the hand and foot followed by the humerus, femur, and tibia. Most lesions are latent after skeletal maturity and are diagnosed incidentally. Fewer than 1% will undergo malignant transformation into chondrosarcomas. Management of an asymptomatic lesion includes observation only with serial radiographs.

Weiner et al described the radiographic concerning features that would suggest chondrosarcoma transformation and these included: lucency developing within the calcification, periosteal reaction, and soft-tissue mass all of which require referral to an oncologic orthopedist.

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