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A 5-year-old boy has a history of bilateral dislocated radial heads, bilateral knee dislocations, and flattened facies. What other important orthopaedic-related condition must be checked in this patient?
congenital vertical talus
congenital trigger thumb
congenital pseudoarthrosis of clavicle
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Larsen’s syndrome is characterized by multiple dislocated joints, including hip, knee, elbow/radial head, foot deformities, scoliosis, and potentially lethal cervical kyphosis. It is important to obtain screening radiographs of the cervical spine in these patients to identify kyphosis and prevent neurologic complications. Progressive kyphosis may require cervical fusion. In addition to the orthopaedic manifestations, patients can also have laryngeal or tracheal problems, lesions of the heart valves, or aorta, and hyperelasticity syndromes that present as hypotonia.
Laville JM, Lakermance P, Limouzy F
J Pediatr Orthop. 1994 Jan-Feb;14(1):63-73. PMID: 8113375 (Link to Abstract)
Laville, JPO 1994
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