Summary Intersection syndrome is an inflammatory condition that occurs at the crossing point of the 1st dorsal compartment (APL and EPB ) and the 2nd dorsal compartment (ECRL, ECRB). Diagnosis is made clinically with pain over the dorsoradial forearm (5 cm from wrist joint) made worse with resisted wrist extension and thumb extension. Treatment is conservative with rest, wrist splinting and steroid injections. Epidemiology Incidence rare login to view 1 more bullet Demographics males = females Risk factors rowing skiing horseback riding weight lifting Etiology Pathophysiology mechanism is repetitive wrist extension login to view 2 more bullets Anatomy Extensor tendon compartments Compartment 1 (De Quervain's Tenosynovitis ) login to view 2 more bullets Compartment 2 (Intersection syndrome) login to view 2 more bullets Compartment 3 login to view 1 more bullet Compartment 4 login to view 2 more bullets Compartment 5 (Vaughan-Jackson Syndrome ) login to view 1 more bullet Compartment 6 (Snapping ECU ) login to view 1 more bullet Presentation Symptoms pain over dorsal forearm and wrist Physical exam tenderness on dorsoradial forearm login to view 1 more bullet provocative tests login to view 1 more bullet Imaging Radiographs not required for the diagnosis or treatment of intersection syndrome MRI indications login to view 1 more bullet views login to view 1 more bullet findings login to view 2 more bullets Differential De Quervain's tenosynovitis Wartenberg's syndrome Diagnosis Clinical diagnosis is made with careful history and physical examination Treatment Nonoperative rest, wrist splinting, steroid injections login to view 4 more bullets Operative surgical debridement and release login to view 4 more bullets