3.6 of 22 Ratings
A 25-year-old female presents to the emergency room within increasing left shoulder pain after walking into a door 5 months ago. She previously sustained a femoral fracture 2 years ago after tripping on a rug. Relevant skeletal survey radiographs and tissue biopsy results are shown in Figures A through D. Laboratory investigations show normal glomerular filtration rate and creatinine clearance. Dual energy x-ray absorptiometry (DEXA) scan shows T-score of -1.4 and -1.2 at the hip and lumbar spine, respectively. Which of the following laboratory values in Figure E most likely reflects this patient's condition?
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A 35-year-old female complains of 1 month of right hip pain during ambulation. Her medical history includes end-stage renal disease for which she is on hemodialysis three times per week. A radiograph of the right hip, spine, and skull are shown in Figures A-C. Figure D shows a histology microphotograph of a biopsy specimen. All of the following laboratory findings are associated with this condition EXCEPT?
Decreased 1,25-(OH)2-vitamin D3
Increased alkaline phosphatase