Synovium Function mediates nutrient exchange between blood and joint fluid Composition vascularized connective tissue is porous and lacks basement membrane cell types type A cells login to view 4 more bullets type B cells login to view 5 more bullets type C cells login to view 3 more bullets Synovial Fluid Function lubricates articular cartilage and provides nourishment through diffusion Origin made from a ultrafiltrate of blood plasma regulated by synovium login to view 1 more bullet Consists of hyaluronin uridine diphosphoglucose dehydrogenase enzyme critical for its synthesis lubricin a key lubricating glycoprotein reduces coefficient of friction within the joint proteinase urokinase-type plasminogen activator login to view 1 more bullet collagenases prostaglandins Biomechanics synovial fluid exhibits non-Newtonian flow characteristics the viscosity coefficient is not a constant the fluid is not linearly viscous viscosity increases as the shear rate decreases