composition of bone Bone is made up of organic component 40% of dry weight inorganic component 60% of dry weight Organic component Components include collagen 90% of organic component primarily type I collagen provides tensile strength it is a triple helix composed of one alpha-2 and two alpha-1 chains proteoglycans responsible for compressive strength inhibit mineralization composed of glycosaminoglycan-protein complexes matrix proteins includes noncollagenous proteins function to promote mineralization and bone formation login to view 21 more bullets cytokine and growth factors small amounts present in matrix aid in bone cell differentiation, activation, growth, and turnover include login to view 1 more bullet Inorganic component Components include calcium hydroxyapatite (Ca10(PO4)6(OH)2 provides compressive strength osteocalcium phosphate (brushite)