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Which of the following is a characteristic change in cartilage involved in moderate osteoarthritis?
Decreased thickness of subchondral bone
Decreased chondrocyte activity
Increased proteoglycan quantity
Increased water content
Increased collagen quantity
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Which of the following characteristics of stromelysin is incorrect?
Belongs to the family of proteolytic enzymes called metalloproteinases
Secreted by chondrocytes
Inhibited by Tissue Inhibitor of Metalloproteinase
Inhibited by plasmin
Degrades cartilage and is thought to play a role in degenerative joint disease