Raynaud's Syndrome

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Topic updated on 05/06/12 6:08pm
Introduction
  • Raynaud's Syndrome consists of both
    • Raynaud's Phenomenen
      • vasospastic disease with known cause
    • Raynaud's Disease
      • vasospastic disease with no known cause (idiopathic)
 
Raynaud's phenomenen
  • Introduction
    • sasospastic disease with a known underlying disease including
      • connective tissue disease
        • scleroderma (80-90% incidence of Raynaud's phenomen)
        • SLE (18-26%)
        • dermatomyositis (30%)
        • RA (11%)
      • CREST syndrome
        • chondrocalcinosis, Raynaud's, esophogeal dysmotility, sclerodactytly, telangiectasis
      • neurovascular compression (thoracic outlet syndrome)
    • patients are generally older than patients with Raynaud's disease
  • Presentation
    • symptoms
      • asymetric
    • physical exam
      • peripheral pulses often absent
      • trophic changes of skin
  • Treatment
    • directed at underlying cause
    • smoking cessation and avoidance of cold exposure critical 
Raynauds disease
  • Vasospastic disease with no known cause (idiopathic)
    • seen in young premenopausal woman
    • diagnosis bases on Allen and Brown criteria
Allen and Brown criteria for Raynaud's Disease
  • Intermittent attacks of discolration of the acral parts
  • Bilateral involvement
  • Abscence of clinical arterial occlusion
  • Gangrene or atrophic changes are rate
  • Symptoms present for 2 years
  • Abscence of other disease which could explain
  • Predominance in woman
  • Presentation
    • symptoms often bilateral
    • pulses usually present
  •  Treatment
    • nonoperative
      • medical management
        • indicated as first line of treatment
        • modalities
          • smoking cessation and avoidance of cold exposure critical
          • medications to include
            • calcium channel blockers
            • ASA
            • intra-arterial reserpine
    • operative
      • digital sympathectomy
        • indicated in severe cases that failed conservative treatment
      • microvascular reconstuction
        • may be indicated in rare situations

 

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