summary Squamous Cell Carcinoma is a malignant soft tissue tumor most commonly found in elderly patients. Diagnosis is made with a biopsy. Treatment is wide surgical resection with or without radiation and skin grafting. Epidemiology Anatomic location dorsum of hand and forearm most common subungual malignancy Riisk factors primary risk factor is excessive exposure to ultraviolet radiation actinokeratosis chronic osteomyelitis Marjolin's ulcer is a squamous cell carcinoma resulting from chronic draining wounds or burn scars Presentation Symptoms pain Imaging Radiographs recommended views AP and lateral of affected area findings lytic lesion Differential Differential of Squamous Cell Carcinoma Treated with wide-resection alone Squamous cell o Adamantinoma o Chordoma o Chondrosarcoma o Parosteal osteosarcoma o Treatment Operative wide surgical resection +/-skin graft +/- radiation indications standard traditional treatment adjunctive radiation indications lesions >2cm wide 4mm deep perineural invasion lymph node metastases Mohs microsurgery indications becoming more popular smaller lesions highest cure rate technique lymph node biopsy may be necessary Prognosis Metastasis lymph node metastases and high histologic grade confer poor prognosis higher metastatic potential than basal cell carcinoma
QUESTIONS 1 of 4 1 2 3 4 Previous Next Sorry, this question is for PEAK Premium Subscribers only Upgrade to PEAK (OBQ10.190) Which of the following best describes a squamous cell carcinoma that develops as a result of chronic drainage from sinus tracts or a result of burn scars? QID: 3288 Type & Select Correct Answer 1 Cushing's ulcer 3% (70/2314) 2 Mooren's ulcer 1% (30/2314) 3 Chancroid ulcer 2% (52/2314) 4 Marjolin's ulcer 88% (2028/2314) 5 Curling's ulcer 5% (124/2314) L 1 Question Complexity C Question Importance Select Answer to see Preferred Response SUBMIT RESPONSE 4 Review Tested Concept Review Full Topic Sorry, this question is for PEAK Premium Subscribers only Upgrade to PEAK Sorry, this question is for PEAK Premium Subscribers only Upgrade to PEAK