Updated: 7/23/2015

Undifferentiated Pleomorphic Sarcoma

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https://upload.orthobullets.com/topic/8064/images/mfh histo.jpg
Introduction
  • A malignant fibrogenic tumor that occurs in patietns from 30-80 years of age
    • similar to fibrosarcoma of soft tissue in presentation and treatment
Symptoms
  • Presentation
    • usually and enlarging painless mass
    • usually symptoms develop after mass reaches ten cm
Imaging
  • Radiograph are usually normal
  • MRI shows deep seated inhomogeneous mass
Histology
  • Classic characteristics are
    • spindle and histiocytic cells arranged in stroiform (cartwheel) pattern
    • chronic inflammatory cells may be present
Treatment
  • Operative
    • wide local resection and adjuvant radiation 
      • technique
        • add radiation if tumor is > 5 cm (5000 cGy before resection and 2000 cGy after resection)
        • may do local adjuvant treatment with phenol or cryotherapy
IBank
  Location
Xray
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CT
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MRI
Histo(1)

Case A

tibia
 
 
 
(1) - histology does not always correspond to case 


 

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