Compression of the ulnar nerve within Guyon's canal, termed ulnar tunnel syndrome, is most commonly caused by a ganglion cyst. A lack of dorsal ulnar sensory deficit helps differentiate entrapment here from at the elbow because the dorsal ulnar cutaneous nerve branches proximal to Guyon's canal. The clinical photo demonstrates Froment's sign where the FPL is used to substitute for the weakened adductor pollicis resulting in flexion of the thumb at the interphalangeal joint, and MCP joint hyperextension. The AIN can be compressed by the accssory head of the FPL (Gantzer's muscle) which results in loss of FPL, index FDP and PQ motor function and no sensory deficits. Ulnar nerve compression at Osborne's ligament, the two heads of the FCU, or by the anconeus epitrochlearis will classically result in volar and dorsal ulnar sensory loss of the affected hand.
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