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3.2 of 12 Ratings
A 63-year-old man presents with an enlarging mass in his left thigh. Radiographs and an MRI are shown in Figures A, B, and C. A biopsy is performed and returns with the histology shown in Figure D. Which of the following is the best next step in treatment?
Marginal resection and radiation
Wide resection and chemotherapy
Wide resection and radiation
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A 64-year-old man presents with forearm swelling. A gadolinium-enhanced MRI of his forearm is shown in Figure A and a CT scan of his chest is shown in Figure B. The lesion is resected and its gross and cellular histological appearance is shown in Figure C and D respectively. Fluorescence-in-situ-hybridization is negative for t(X:18) and t(12:16). Immunohistochemistry is negative for desmin, myogenin and CD34. What is the most likely pathologic diagnosis?
High-grade pleomorphic undifferentiated sarcoma