Based on the Enneking classification of tumor resections, this would be classified as a intra-lesional resection as there are residual tumor cells in the resection margin of the femur. Intra-lesional resections occur in the lesion, as in this case, and are not appropriate for malignant sarcomas. For osteosarcomas, it is common to "sample" the marrow margin at the level of the bone cut during resection.
The referenced article by Enneking is the original description of resection margins used in soft tissue sarcomas. Because this referenced article was published when the surgical treatment for soft tissue sarcomas didn't include adjuvant therapy, the results aren't as applicable today. Today with adjuvant therapy, many sarcomas which are close to neurovascular structures can be safely resected without sacrifice of these critical structures.
Answer 2: The Enneking classification does not use the term inter-lesional.
Answer 3: Wide resections are those where the tumor compartment is maintained but a "cuff" of normal tissue surrounds the resected specimen. If you think of the tumor as the fruit of an orange, a wide resection takes a normal cuff of tissue (the rind) around the tumor in 360 degrees (Illustration A).
Answer 4: Marginal resections are those which occur through the periphery of the tumor in the zone of the pseudocapsule where tumor cells can be located.
Answer 5: Radical resections are those in which the entire "compartment " of the tumor is removed. In the case of Illustration A, a radical resection would require removal of the entire femur as that is the "compartment".
Menendez JR, ed. OKU: Musculoskeletal Tumors. 2002. American Academy of Orthopaedic Surgeons. Rosemont, IL.
Enneking WF, Spanier SS, Malawer MM. The effect of the Anatomic setting on the results of surgical procedures for soft parts sarcoma of the thigh. Cancer. 1981 Mar 1;47(5):1005-22.
PMID:7226034 (Link to Abstract)