Please confirm topic selection

Are you sure you want to trigger topic in your Anconeus AI algorithm?

Please confirm action

You are done for today with this topic.

Would you like to start learning session with this topic items scheduled for future?

Updated: Jun 22 2021

Basal Cell Carcinoma

  • summary
    • Basal Cell Carcinoma is the most common skin malignancy that rarely, if ever, metastasizes.
    • The condition most commonly occurs in patients with significant sun exposure, who present with a pink, pearly-white, dome-shaped nodule.
    • Diagnosis is made with a biopsy showing basophilic palisading cells.
    • Treatment is usually wide surgical resection. 
  • Epidemiology
    • Risk factors
      • sun exposure
      • prior ionizing radiation
      • xeroderma pigmentosum
      • common in fair-skinned individuals
    • Anatomic location
      • commonly affects upper lip (squamous cell carcinoma typically affects lower lip)
  • Presentation
    • Symptoms
      • typically asymptomatic, but may be tender if ulcerated
      • slow-growing
    • Physical exam
      • pink, pearly-white, almost translucent dome-shaped nodule or papule
      • overlying telangiectasias
      • commonly develop raised or rolled border
      • commonly ulcerate, bleed, and crust in the center (a non-healing ulcer)
      • frequently on sun-exposed areas
  • Evaluation
    • Diagnosis by skin biopsy
      • basophilic palisading cells on histology
      • nests of basaloid cells in dermis
  • Differential
    • Squamous cell carcinoma
    • Actinic keratosis
  • Treatment
    • Prevention
      • use sunscreen
      • avoid sun exposure
    • Surgical
      • electrodesiccation and curettage
        • indications
          • typically for non-facial tumors that are small or superficial – not used for aggressive tumors
          • best technique determined by
            • size
            • location
            • histology
            • cosmetic considerations
        • outcomes
          • cure rate up to 92%
      • Mohs micrographic surgery
        • indications
          • especially if on face or if recurrence
        • outcomes
          • cure rate up to 99%
      • wide local surgical excision
        • outcomes
          • cure rate up to 90%
  • Prognosis
    • If treated, typically very good
    • Risk of developing another basal cell carcinoma is 5-8% per year
1 of 0
Private Note

Attach Treatment Poll
Treatment poll is required to gain more useful feedback from members.
Please enter Question Text
Please enter at least 2 unique options
Please enter at least 2 unique options
Please enter at least 2 unique options