Review Question - QID 215768

A healthy and athletic 13-year-old female presents for evaluation of worsening left knee pain. She first noticed the pain approximately one month ago when competing in a club soccer tournament, but now the pain is present at rest and during the night. She can no longer play soccer and her parents think that she may have strained a muscle. Figures A through F are the radiographs, contrast MRI, low power histology, and high power histology of her lesion. What is the most appropriate adjuvant systemic treatment protocol in addition to surgical resection?