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Which statement most accurately describes the physiology of peripheral nerve regeneration following an axonotmesic lesion?
The proximal nerve segment undergoes Wallerian degeneration
Axon growth occurs from the distal segment to proximal segment
Neurotrophic factors direct phagocytic activity
Proximal axon budding allows for antegrade (or distal) axon migration
Axoplasm and myelin are degraded distally predominantly by Schwann cells for the first 12 months following injury
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The patient sustains the injury seen in Figure A from a gunshot injury. The physical exam is notable for lack of sensation in his fourth and fifth digits as well as a positive Froment's sign. Which of the following factors has not been shown to be a significant prognostic indicator of functional recovery following nerve repair?
Duration to time of repair
Length of repair
Postoperative physical rehabilitation
Type of autograft used
A 55-year-old male laborer comes in with a chief complaint of clumsiness with his right hand for the past 3 months including difficulty using a hammer while at work. He has had no injury to the right upper extremity. On physical examination, he has persistent small finger abduction/extension with finger extension and active adduction. An EMG is performed and demonstrates ulnar nerve conduction velocities of 31 m/sec (normal >52m/sec). The patient symptoms are most accurately described as
Axonotmesis with ischemia origin
Axonotmesis with myelin disruption
Neurapraxia with ischemia origin
Neurapraxia with endoneurium disruption
You are seeing a 24-year-old male in the emergency room after he was involved in a knife fight. He has severed the common digital nerve to the index finger on his dominant hand, with an 8mm gap between nerve ends. In counseling him about repair, which of the following options is as good as autologous nerve grafting?
Glycolide trimethylene carbonate conduit
Primary end-to-end repair
Polyglycolic acid conduit
Which of the following nerves has the most favorable regenerative potential in restoring motor function after a graft repair within half a year after being injured?
Axon regeneration almost always occurs following a Sunderland second-degree nerve injury because which anatomic structure is not injured?
Vitamin B12 deficiency is a known cause of which the following?
Inability to whistle
Peripheral sensory neuropathy
Increased deep tendon reflexes
Which of the following structures are slowly adapting skin receptors that detect pressure, texture, and low frequency vibration and are best evaluated by static two-point discrimination?
Free nerve endings
Which of the following peripheral nerve structures functions to cushion the nerve against external pressure?
Peripheral Nerve Injury and Repair Options– Eric Hentzen, M.D.(COA 2017, 5.1)
The medial antebrachial cutaneous (MABC) nerve is a viable donor for nerve graft...
2012 CRN - Acute Nerve Injury and Repair - Presentation Part 1 - Peripheral Nerv...
HPI - 29 year old male with laceration to volar distal forearm from breaking glass with arm.
When examining the nerve ends after a traumatic laceration, how do you determine if there is healthy nerve tissue on each end of the nerve?