Review Question - QID 1362

The epineurium is a supportive sheath surrounding peripheral nerves that cushions fascicles against external pressure. It is comprised of a loose meshwork of collagen and elastin fibers that are aligned parallel with the nerve fibers.

Illustration A & B depicts the contents of a nerve including epineurium, perineurium, and endoneurium.

Incorrect Answers:
Answer 1: Endoneurium is a fibrous tissue that covers the axon, Schwann cell, and myelin of each nerve fiber.
Answer 2: Fibronectin and laminin are extracellular matrix glycoproteins that facilitate directional nerve fiber branching.
Answer 3: N-cadherin is an adhesive membrane glycoproteins on neural ectoderm and facilitate growing axons.
Answer 4: Perineurium is a dense connective tissue which surrounds nerve fascicles. It provides high tensile strength. The perineurium also limits diffusion within the intraneural environment and subsequently prevents injury from edema.