The somites are mesodermal in origin; somites eventually form dermis (dermatome), skeletal muscle (myotome), sclerotome or cartilage, tendons, and endothelial cells. The sclerotome of the somites develops into the axial skeleton. The neural crest forms the peripheral nervous system, the lateral plate mesoderm becomes the dermis, and the dorsal myotome (epimere) becomes the dorsal muscles.
Illustration A depicts the sclerotome of the somites development into the vertebra. The nucleus pulposus forms from the notochord and the annulus fibrosus forms from the sclerotome.
Buckwalter JA, Einhorn TA, Simon SR (eds): Orthopaedic Basic Science: Biology and Biomechanics of the Musculoskeletal System, ed 2. Rosemont, IL, American Academy of Orthopaedic Surgeons, 2000, pp 77-109
Sadlet TW, Langman J: Langman’s Medical Embryology, ed 8. Philadelphia, PA, Lippincott Williams & Wilkins, 2000, Chapter 9