Updated: 6/22/2021

Fibrosarcoma of Soft Tissue

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  • summary
    • Fibrosarcoma of Soft tissue is a malignant fibrogenic tumor that occurs in patients between 55-80 years of age.
    • Diagnosis is made with a biopsy showing spindle-shaped cells with scant cytoplasm and indistinct borders with tissue that is organized in herringbone fashion.
    • Treatment is usually wide local resection with radiation
  • Symptoms
    • Presentation
      • usually and enlarging painless mass
      • usually symptoms develop after mass reaches ten cm
  • Imaging
    • Radiograph
      • are usually normal
    • MRI
      • shows deep seated inhomogeneous mass
  • Histology
    • Classic characteristics are
      • fasiculated growth pattern
      • spindle-shaped cells with scant cytoplasm and indistinct borders
      • cells separated by interwoven collagen fibers
      • tissue may be organized in herringbone fashion
  • Treatment
    • Operative
      • wide local resection with perioperative radiation
        • indications
          • most cases
        • radiation
          • add radiation if tumor is > 5 cm (5000 cGy before resection and 2000 cGy after resection)
        • local adjuvant treatment
          • may do local adjuvant treatment with phenol or cryotherapy

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