Updated: 6/22/2021

Nodular Fasciitis

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  • summary
    • Nodular Fasciitis is a common, fibrous, soft tissue lesion that usually occurs in the upper extremities of young people.
    • Diagnosis is made with MRI studies showing a deep-seated inhomogeneous mass with nodularity along the fascial planes. Biopsy shows short irregular bundles and fascicles in a dense reticulum network.
    • Treatment is usually marginal surgical resection. 
  • Epidemiology
    • Incidence
      • most common fibrous soft tissue lesion
      • half of the cases occur in the upper extremities
    • Demographics
      • males and females equally affected
    • Anatomic location
      • volar forearm, back, chest wall, head and neck
  • Presentation
    • Symptoms
      • may be painless or painful
        • painful in half of patients
      • often rapidly enlarging mass over 1 to 2 weeks
      • lesions 1 to 2 cm
  • Imaging
    • Radiograph
      • usually normal
    • MRI
      • shows deep seated inhomogeneous mass
      • nodularity with extension along the fascial planes
      • avid enhancement with gadolinium
      • most commonly is superficial but can occur intramuscularly or along the superficial plane
  • Histology
    • Classic characteristics are
      • short irregular bundles and fascicles
      • dense reticulum network
      • small amounts of mature collagen
  • Treatment
    • Operative
      • marginal resection
  • Differential
    • Differential of Nodular Fasciitis
      Treated with marginal excision
      Nodular fasciitis (soft tissue)

      Periosteal chondroma

      Neurilemoma (soft tissue)

      Epidermal inclusion cyst

      Glomus tumor

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