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Review Question - QID 772

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QID 772 (Type "772" in App Search)
A 70-year-old female has unrelenting lower back pain and severe left anterior thigh pain. She has hip flexion weakness on the left that is limiting her ambulation. A representative image from her abdominal CT is shown below as well as a sagittal MRI of her spine. Nonoperative management has failed. What is the next appropriate step before performing an anterior corpectomy and stabilization of the spine?
  • A
  • B

CT-guided biopsy of spinal lesion

25%

283/1117

Percutaneous kyphoplasty

1%

8/1117

External beam radiation

3%

39/1117

Intravenous antibiotics

1%

14/1117

Arteriography and embolization of the spinal lesion

69%

769/1117

  • A
  • B

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The CT of the abdomen shows a renal mass. Renal cell carcinoma is extremely hypervascular and has a propensity to bleed profusely. Thus, many authorities recommend arteriography and embolization of the lesion prior to performing any surgery on a suspected renal metastatic lesion. The goal is to reduce blood loss in patients undergoing surgery for these hypervascular tumors. There is no need for a CT guided biopsy for several reasons: 1) because our suspicion is high for metastatic renal disease 2) decompression is indicated and we can obtain a biopsy during decompression 3) biopsies of metastatic renal lesions can lead to excessive bleeding. Percutaneous kyphoplasty and radiation would not alleviate her radicular symptoms and are not indicated. Her clinical picture and MRI are not characteristic of infection, and therefore antibiotics would not be indicated.

Sundaresan et al performed a case-control study of patients with renal mets to the spine treated with radiation alone or surgery +/- radiation. The median survival of the surgically treated patients was 13 months, compared with 3 months for those treated by radiation alone. In addition, a greater proportion of the surgically treated patients were benefitted neurologically (70%) compared with those treated by radiation (45%).

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