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Resection of the distal femur and postoperative chemotherapy
8%
23/296
Preoperative chemotherapy followed by radiation therapy, then resection of the distal femur
3%
8/296
Preoperative chemotherapy followed by surgical resection of the lesion and postoperative chemotherapy
79%
233/296
Preoperative chemotherapy followed by radiation therapy, resection of the distal femur, then postoperative chemotherapy
24/296
Resection of the distal femur followed by radiation therapy
2%
7/296
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This is a classic appearance for an osteosarcoma. The radiographs reveal a mixed osteolytic and osteoblastic lesion in a skeletally immature patient in the distal right femoral metaphysis. The pain pattern with progressive symptoms leading to the presence of night pain is also typical for this condition. The biopsy specimen reveals pleomorphic cells and the presence of osteoid. The current standard of care in the treatment of osteosarcoma is neoadjuvant chemotherapy followed by surgical resection or amputation followed by additional postoperative chemotherapy. Osteosarcoma is not radiosensitive.
3.9
(8)
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