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Updated: Jan 2 2023

Juvenile Idiopathic Arthritis

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  • summary
  • Epidemiology
  • Etiology
    • Genetics
      • HLA markers
        • DR4 associated with polyarticular
        • DR8, DR5, DR2.1 associated with pauciarticular
      • RF- seropositive in <15%
    • Diagnostic criteria
      • a diagnosis of exclusion
        • must rule out infection
      • one of the following must be present to make diagnosis
        • rash
        • presence of RF
        • iridocyclitis
        • C-spine involvement
        • pericarditis
        • tenosynovitis
        • intermittent fever
        • morning stiffness
    • Associated conditions
      • C-spine involvement
        • may lead to kyphosis, facet ankylosis, and atlantoaxial subluxation
      • Ocular involvement
        • typically consists of iridocyclitis, a type of anterior uveitis
        • frequently indolent and requires immediate ophthalmologic evaluation for slit lamp examination
        • can lead to rapid loss of vision if untreated
        • increase risk with positive ANA titer
      • Stills disease
        • acute-onset JRA with multiple joint involvement, fever, rash, and splenomegaly
        • infection must be ruled out
        • male = female
        • usually presents at age 5-10 years
  • Classification
  • Presentation
  • Imaging
  • Studies
  • Treatment
  • Prognosis
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Basic Science⎪Juvenile Idiopathic Arthritis
  • Basic Science
  • - Juvenile Idiopathic Arthritis
21:42 min
4/28/2020
576 plays
5.0
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