Dense myofibroblast networkFibroblasts align along tension lines and produce more collagenIncrease ratio of type III to type I col
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A 50-year-old patient presents with stiffness in her hand. A clinical photo is shown in Figure A. During surgical exposure, the neurovascular bundle is identified and dissected. What is the clinically most important pathologic structure to identify and what is its location relative to the neurovascular bundle in the digit?
Spiral cord which is central and superficial to the neurovascular bundle
Central cord which is midline and superficial to the neurovascular bundle
Retrovascular cord which is central and superficial to the neurovascular bundle
Spiral cord which is lateral and deep to the neurovascular bundle
Central cord which is lateral and deep to the neurovascular bundle
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Which of the following patients with Dupuytren's contracture would benefit the most from dermatofasciectomy and full-thickness skin grafting opposed to traditional fasciectomy?
70-year-old sedentary male with small finger involvement isolated to the MCP joint
50-year-old male systems analyst with ring and small finger involvement limited to the MCP joints
65-year-old female golfer with ring and small finger involvement including MCP and PIP joints
40-year-old female stenographer with middle, ring, and small finger involvement including MCP and PIP joints with 50 and 55 degree contractures of ring and small finger MCP joints, respectively
None of the above as no difference in outcome has been demonstrated between the two procedures
All of the following have been implicated in the pathogenesis of Dupuytren's contracture EXCEPT?
Fibroblast growth factor (FGF)
Transforming growth factor- beta (TGF-beta)
Platelet-derived growth factor (PDGF)
What is the name of the pathologic structure, identified by the white arrow in Figure A, that displaces the digital neurovascular bundle and places it at risk during during surgical treatment of Dupuytren's disease?