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Practice contact
(612) 313-0520
600 Hennepin Ave
Suite 310
Minneapolis Minnesota 55403
John Sperling MD
Orthopaedic Surgeon - General Specialty
Surgeon - 30 years in practice
Primary Practice: Mayo Clinic - Rochester, MN
Primary Hospital: Mayo Clinic Hospital Methodist Campus

Practice Contact

Office Address
600 Hennepin Ave
Suite 310
Minneapolis Minnesota 55403
(612) 313-0520

Clinical Expertise

Shoulder & Elbow Surgery Hip & Knee Surgery Rotator Cuff Surgery Shoulder Arthroscopy Shoulder Replacement Shoulder Replacement Revision


The research of John W. Sperling, M.D., is focused on shoulder disorders, which are a major burden on the health care system. Dr. Sperling works with a multidisciplinary team of researchers to develop innovative strategies for the treatment and prevention of shoulder disorders. Focus areas: Rotator cuff disease. Together with a multidisciplinary team, Dr. Sperling has made substantial progress in understanding rotator cuff disease and has identified novel treatment strategies to help patients who have these conditions. Shoulder arthritis. Dr. Sperling has one of the largest referral practices worldwide for the treatment of shoulder arthritis. This unique practice has helped drive the understanding and development of innovative treatment modalities to help patients with the pain and loss of quality of life associated with shoulder arthritis. Significance to patient care. Rotator cuff disease and shoulder arthritis represent some of the most common conditions for which patients seek medical attention. Currently, there are very few options to reverse the course of these disease processes. Dr. Sperling and a team of scientists have already identified several promising molecular pathways to help patients with these problems. This unique team of basic science researchers and clinicians is well-positioned to translate these exciting findings into improvement in inpatient care.
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Primary Practice

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Primary practice
Mayo Clinic - Rochester, MN

Hospital Affiliations

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Mayo Clinic Hospital Methodist Campus
(507) 284-2511
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Mayo Clinic Hospital Rochester
(507) 255-5120

Education & Training

The Hospital for Special Surgery
Mayo Graduate School of Medicine
University of Virginia School of Medicine
University of Virginia
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