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Accurate graft size
61%
454/748
Donor cell viability
13%
95/748
Reestablishment of the central meniscal blood supply
16%
116/748
Suppression of the immune response
4%
31/748
Cryopreservation of the donor graft
7%
49/748
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Success of a meniscal allograft transplantation is strongly dependent on accurate graft sizing, typically within 5% of the native meniscus. Previous studies have established that donor cell viability is not mandatory for the survival of these grafts since they are replaced by the recipient’s cells (at least peripherally) within several weeks. Thus, cryopreservation of the graft to ensure cell viability is not necessary. There is a limited immune response to musculoskeletal allografts; therefore, immunosuppression, as is required for visceral organ transplantation, is not indicated.
3.3
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