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Review Question - QID 8071

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QID 8071 (Type "8071" in App Search)
A 45-year-old woman with type 2 diabetes (BMI 38, Hgb A1c 7.4) has a grade II ulcer under the first metatarsal head. Previous treatment with a custom orthosis and total contact casting has provided only temporary healing. Her ankle-brachial index is 0.95, she has no foot deformity, and there is no evidence of infection. What is the next most appropriate step in management?