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Review Question - QID 7165

TKA Polyethylene Wear & Manufacturing Polyethylene sterilization Radiation QID: 7165 (SAE10BS.77)
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QID 7165 (Type "7165" in App Search)
Crosslinking of ultra-high molecular weight (UHMW) polyethylene has been shown to increase its resistance to wear, both in laboratory studies and in up to 10 years of clinical use. As the crosslinking dose is increased above the traditional range for gamma radiation sterilization (ie, 2.5 to 4 Mrads), wear resistance progressively increases. What is the principal negative effect of increasingly high crosslinking?
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