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Review Question - QID 7108

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QID 7108 (Type "7108" in App Search)
Following spinal cord injury (SCI), methylprednisolone (a bolus of 30 mg/kg plus 5.4 mg/kg per hour over 24 hours) initiated within 8 hours of injury has been associated with which of the following MRI findings?

Decreased extent of cord edema only

34%

89/260

Decreased extent of cord hemorrhage only

12%

30/260

Decreased extent of both cord edema and hemorrhage

4%

10/260

Increased extent of cord hemorrhage but decreased edema

2%

5/260

No difference in extent of hemorrhage and edema

47%

122/260

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MRI findings following SCI treated with high dose steroids have demonstrated that the steroids are associated with a lower extent of cord hemorrhage. No difference in cord edema was found. The decreased cord hemorrhage seen with use of high dose steroid adminstration in this setting has not correlated with improved clinical outcomes.

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