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Review Question - QID 661

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QID 661 (Type "661" in App Search)
What is the mechanism of action of vancomycin?

inhibition of cell wall synthesis

80%

2768/3461

increase cell wall permeability

8%

284/3461

ribosomal inhibition

6%

197/3461

interference with DNA metabolism

5%

179/3461

antimetabolite action

1%

21/3461

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Vancomycin is an inhibitor of cell wall synthesis and is bactericidal for gram positive organisms. Antibiotics exert their effects via five basic mechanisms: (1) Inhibition of cell wall synthesis (cephalosporins, penicillins, vancomycin, imipenem). (2) Increasing cell membrane permeability (Bacitracin). (3) Ribosomal inhibition (gentamycin, erythromycins, linezolid, tetracyclines). (4) interference with DNA metabolism (quinolones), and (5) antimetabolite action (Trimethoprim).

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