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Review Question - QID 513

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QID 513 (Type "513" in App Search)
Using levels of evidence in research studies, which of the following represents a level II study?

Retrospective case control study

9%

208/2353

Prospective cohort study

81%

1897/2353

Case report of 3 patients with the same disease

1%

30/2353

High-quality randomized prospective clinical trial

9%

203/2353

The opinion of a review panel at the annual AAOS meeting

0%

8/2353

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Level II Evidence includes prospective cohort studies. There are 5 levels of evidence in clinical research. Level I includes randomized clinical trials. Level II includes prospective cohort studies. Level III includes case control studies AND retrospective cohort studies. Level IV includes case series. Level V evidence includes expert opinion, case reports, and personal observation. The cited reference by Bernstein et al is an excellent review of Evidence Based Medicine (EBM) and describes the 5 step process of making medical decisions based on the available, and often limited, evidence. These steps include: 1) Formulate answerable questions. 2) Gather the evidence. 3) Appraise the evidence. 4) Implement the evidence. 5) Evaluate the process. The reference by Spindler et al is another review article that discusses the different levels of evidence for different study types.

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