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Review Question - QID 502

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QID 502 (Type "502" in App Search)
All of the following are risk factors for wear-related failure in total knee arthroplasty when using a polyethylene liner that underwent sterilization via gamma irradiation in air EXCEPT?

Increasing shelf age of polyethylene liner

8%

156/1893

Younger age of patient

2%

36/1893

Male gender

10%

186/1893

Posterior cruciate retaining knee design

71%

1352/1893

Use of a rough tibial baseplate

8%

151/1893

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Increasing shelf age, younger age, male gender, and a rough tibial baseplate are all risk factors for wear-related failure in total knee arthroplasty when using a polyethylene liner. Posterior cruciate retaining knee design is not a documented risk factor.

Fehring et al reviewed 2091 TKA using the Press fit condylar system and noted that the 13-year survivorship for all patients was 82.6% with a 8.3% prevalence of wear-related failure. Cox hazards analysis revealed five variables that were correlated with wear-related failure: patient age, patient gender, polyethylene sheet vendor, polyethylene finishing method, and polyethylene shelf age. They were unable to identify one factor as the defining reason for these wear-related failures. They cautioned that these findings may only be specific to inserts that underwent sterilization via gamma irradiation in air.

Collier et al followed 365 TKA (PCL-retaining) for 5-10 yrs and noted that factors related to polyethylene insert osteolysis included advanced shelf age, sterilization method, and the material from which it was machined. Osteolysis was identified in 34% with an insert that had been gamma-irradiated in air and affixed to a rough baseplate surface, but only 9% when the insert had been gamma-irradiated in an inert gas or not irradiated at all and joined to a polished surface.

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