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Review Question - QID 3561

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QID 3561 (Type "3561" in App Search)
MecA is the bacterial gene which encodes for a penicillin-binding protein that alters the efficacy of beta-lactam antibiotics. Which of the following species of bacteria are known to produce mecA?

Clostridium dificile

1%

22/2886

Clostridium tetani

1%

15/2886

Vancomycin-resistant enterococcus

4%

105/2886

Methicillin-resistant staphylococcus aureus

93%

2678/2886

Streptococcus epidermidis

2%

51/2886

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Methicillin-resistant Staphylococcus aureus is the most common carrier of the mecA gene. This gene may also be found in Staphylococcus aureus and Streptococcus pneumoniae species and provide penicillin resistance for these bacteria. None of the other listed bacteria are known to harbor mecA in their bacterial genome.

Marcotte and Trzeciak review community-acquired MRSA with specific focus on diagnosis and treatment. They discuss the differences between community-acquired and hospital-acquired MRSA. Specifically, they emphasize bacterial gene products like mecA which alter the bacterial susceptibility towards common antibiotics, and provide appropriate treatment options for common MRSA infections.

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