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Graft fixation strength increases linearly with time until subchondral union at 3 months
7%
171/2565
Graft fixation strength initially decreases during the early healing phase, and then increases with subchondral bone healing
84%
2150/2565
Graft fixation strength does not change during the first 3 months following surgery
2%
50/2565
Graft fixation strength is enhanced by early weight bearing
3%
76/2565
Graft fixation strength initially increases over the first 6 weeks, then recedes with bony remodeling
4%
104/2565
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Studies have shown graft fixation strength initially decreases during the early healing phase, and then increases with subchondral bone healing. Following mosaicplasty, appropriate post-operative rehabilitation and weight-bearing status must be based upon the fixation of the osteochondral autograft plugs. In addition, early non-weight bearing motion is important to prevent stiffness and protect the joint surfaces with synovial fluid. Whiteside et al. performed a porcine study evaluating the fixation strength of osteochondral autograft mosaicplasty during the first week following implantation. The graft fixation was notably weaker one week following surgery due to the post-operative response and host remodeling. These results suggest that protected weight bearing should be used until the osteochondral plugs have healed into the subchondral bone, generally by 3 months.
3.2
(17)
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