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Review Question - QID 219994

QID 219994 (Type "219994" in App Search)
A 65-year-old male presents to your clinic for the initial evaluation of chronic right knee pain from osteoarthritis. The patient has been utilizing ibuprofen daily to mitigate his painful symptoms for the past year. The patient is concerned that his chronic utilization of ibuprofen may predispose him to side effects such as gastrointestinal upset and gastric ulcer formation. What is the mechanism by which ibuprofen causes the aforementioned adverse reactions?