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Review Question - QID 219772

Bone Signaling & RANKL Introduction Bone metabolism is a dynamic process that balances bone formation and bone resorption QID: 219772 (SBQ24SM.10)
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QID 219772 (Type "219772" in App Search)
A 20-year-old female sustains an open tibia fracture and is set to undergo intramedullary nail insertion. Before the start of the case, the attending asks you about the mechanism of bone morphogenetic protein-2 (BMP-2) in anticipation of possible utilization of rhBMP-2. What protein complexes with Smad1, Smad5, and Smad8 to affect gene transcription?
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