ORTHO
BULLETS
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Review Question - QID 219408

Articular Cartilage Aging in Articular Cartilage Injury QID: 219408 (SBQ23PA.92)
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QID 219408 (Type "219408" in App Search)
A 19-year-old female presents to the clinic for continued management of vague left knee pain following a soccer injury, which has been recalcitrant to physical therapy and platelet rich plasma injections. She is subsequently sent for an MRI, which demonstrates no ligamentous injury. However, a one by one-centimeter full-thickness cartilaginous defect of the lateral condyle is seen. The patient subsequently undergoes arthroscopic debridement with microfracture. Which mediator is directly responsible for the mechanism of chondrocyte death following her injury?
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