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Review Question - QID 219378

QID 219378 (Type "219378" in App Search)
A 55-year-old male presents to your office with right medial knee pain which has been worsening over the last 5 years. Radiographs demonstrate changes consistent with tricompartmental osteoarthritis. With regards to cartilage changes in osteoarthritis, which of the following increase in the early stages and decrease in later stages?