Review Question - QID 219276

A 31-year-old otherwise healthy male presents with recurrent right knee effusions resulting in chronic pain and inability to participate in recreational sporting activities. Over the last ten years, he has undergone multiple prior arthroscopic debridement procedures (Figures A and B) and an open synovectomy one year ago (Figures C, D, and E). He states that his knee has again become increasingly stiff and painful with overall symptom recurrence. Which of the following would be the most appropriate treatment modality to prevent another local recurrence?