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Review Question - QID 218816

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QID 218816 (Type "218816" in App Search)
A 40-year-old female presents with right leg pain localized to the buttock, posterior thigh, and lateral calf. In addition, she describes numbness and tingling on the dorsum of the right foot. Physical exam shows weakness to EHL. Three months of nonoperative treatment including anti-inflammatory medication, physical therapy, and selective nerve root corticosteroid injections failed to provide lasting relief and pain is still severe in nature. Her MRI is shown in Figures A and B. What would be the most appropriate management at this juncture?
  • A
  • B

Refer the patient to pain management

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Repeat epidural steroid injection

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Transforaminal diskectomy

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Laminotomy and diskectomy

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Spinal fusion with interbody cage and posterior instrumentation

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  • A
  • B

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The patients clinical presentation and imaging studies are consistent with a L5 radiculopathy caused by a right paracentral disc herniation at L4/5 which is compressing the L5 nerve root. Because she has failed nonoperative management a laminotomy and diskectomy would be the most appropriate treatment.

A L4/5 paracentral disc involves the L5 nerve root. The muscles innervated by L5 nerve root include EHL and tibialis anterior, and therefore these patients may present with a "foot drop". While EHL is usually innervated by L5 alone, tibialis anterior has variable innervation by L4 and L5.

Weinstein et al. (SPORT 2 year results) showed as-treated analysis (prospective nonrandomized), discectomy was favorable with quicker improvement in symptoms for patients with surgery. They warn that the SPORT intent-to-treat analysis (prospective randomized) showed no statistical difference between those who had diskectomy vs. those who did not, but this data was disrupted by a very high crossover rate, and therefore most consider the as-treated analysis as a more accurate representation of the true clinical effect of treatment.

Weinstein et al (SPORT 4 year results) showed in the as-treated analysis that patients treated surgically for intervertebral disc herniation showed significantly greater improvement in pain, function, satisfaction, and self-rated progress over 4 years compared to patients treated non-operatively. They found at four years there was no significant difference in work status between the surgical and nonsurgical group.

Weber et al. look at a cohort that was randomized into surgical and non-surgical treatment for lumbar disc herniations. They found the controlled trial showed a statistically significant better result in the surgically treated group at the one-year follow-up examination. After four years the operated patients still showed better results, but the difference was no longer statistically significant.

Illustration A shows the lower extremity dermatomes. Illustration B shows how a laminotomy is used to access the disc and how an paracentral disc will affect the descending nerve root. Illustration C shows the difference between a laminotomy, hemilaminectomy, and laminectomy.

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