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Review Question - QID 174

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QID 174 (Type "174" in App Search)
A 20-year-old man presents with erythema, swelling, and pain at the left sternoclavicular joint shown in Figure A. His temperature is 38.9 degress Celsius, serum WBC is 14,000, and his C-reactive protein is elevated. He reports that he uses IV heroin. A coronal 3D CT scan of the left clavicle is shown in Figure B. Joint aspiration shows many grams stain positive organisms. Which of the following organisms is the most likely pathogen?
  • A
  • B

Propionibacterium acnes

2%

42/1835

Staphylococcus aureus

91%

1663/1835

Group B streptococcus

5%

84/1835

Neisseria gonorrhea

1%

26/1835

Enterococcus coli

0%

9/1835

  • A
  • B

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This patient has sternoclavicular joint septic arthritis with gram positive organisms. Although there is an increased incidence of Pseudomonas aeruginosa infection in IV drug users, S. aureus is still the most common organism.

Ross et al states "Staphylococcus aureus is now the major cause of sternoclavicular septic arthritis in intravenous drug users. Pseudomonas aeruginosa infection in injection drug users declined dramatically with the end of an epidemic of pentazocine abuse in the 1980s."

The referenced article by Goldin et al is from the New England Journal of Medicine reports that all of their cases of SC joint septic arthritis were in intravenous drug abusers and that P. aeruginosa grew out of 3 patients and S. aureus grew out of 1 patient.

A more recent article by Abu Arab et al reported that Staph aureus was most common even in IV drug users. The review article by Higginbotham and Kuhn note that risk factors for SC joint septic arthritis include hemodialysis, immunocompromise, alcoholism, and HIV. Neisseria gonorrhoeae, fungal, and candida present in HIV patients.

Treatment is I&D and appropriate antibiotics, although aspiration and abx have shown some success too. CT and MRI are useful in diagnosis, and open biopsy or aspiration is recommended for definitive diagnosis.

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