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Figure A
81%
1690/2076
Figure B
3%
65/2076
Figure C
4%
88/2076
Figure D
7%
145/2076
Figure E
77/2076
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Figure A shows the most common sites of giant cell tumors in bone, which are the distal radius, sacrum, distal femur, proximal tibia and proximal humerus. Giant cell tumor of bone (GCT) is a benign aggressive tumor typically found in the epiphysis of long bones. 50% of tumors occur around the knee (distal femur or proximal tibia). The sacrum is the most common site in the axial skeleton. GCT is characterized by proliferation of mononuclear stromal cells and the presence of multi-nucleated giant cells with homogenous distribution. Treatment typically involves intralesional curettage with adjuvant treatment (e.g., phenol, hydrogen peroxide, argon beam, etc). Becker et al. looked at the use of adjuvants after curettage in the treatment of giant cell tumor of bone. They found that polymethylmethacrylate as an adjuvant significantly reduced the recurrence rate following intralesional treatment of benign giant cell tumours compared to no adjunct treatment (22% vs 49% respectively). Incorrect Answers: Figure B shows the common sites of Ewing's tumor of bone, which are the femur, pelvis, ribs, and humerus Figure C shows the common sites of chondroblastoma, which are the epiphysis or apophysis of bone (e.g. distal femur or proximal tibia, femoral head, grater trochanter, etc) Figure D shows the common sites of lymphoma of bone, which are the knee, pelvis, and vertebrae. Figure E shows the common sites of Osteoid osteoma of bone, which are the femur, vertebrae, phalanxes, etc.
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