Review Question - QID 1140

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Charcot-Marie-Tooth Disease Etiology Orthopedic manifestations QID: 1140 (OBQ05.254)

QID 1140 (Type "1140" in App Search)

A 17-year-old male complains of a foot deformity that has progressed over the past 1 year. He has pain along the lateral border of his foot with walking. His father has had similar problems with both feet throughout his life. A clinical photograph of the foot is provided in Figure A. Proper management of this patient should include evaluation for which of the following findings?

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Acetabular dysplasia

51%

809/1578

Cervical stenosis

24%

373/1578

Uveitis

11%

169/1578

Hypoplastic thumb

94/1578

Thrombocytopenia

120/1578

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The patients clinical presentation is consistent with Charcot-Marie-Tooth disease (CMT), also known as hereditary motor sensory neuropathy. The cavovarus foot is secondary to peroneus brevis and anterior tibialis weakness. Acetabular dysplasia is known to occur in association with CMT.

Fuller et al review 4 familial cases of CMT. The patients demonstrated cavovarus foot deformities, decreased conduction velocities, acetabular dysplasia, and Trendelenburg gait.

Schwend et al review the evaluation, diagnosis, and treatment of cavus foot deformity in children. Management of the deformity is predicated upon proper diagnosis of the etiology for the cavus foot.