Aneurysmal bone cyst and giant cell tumor of bone have historically been considered benign lesions that can behave in locally aggressive fashion. The clinical and pathologic findings share some common characteristics. When considering a radiographic differential diagnosis, these entities are usually considered together. There are some very distinct differences in potential aggressiveness and in response to treatment. This report summarizes current knowledge regarding these lesions when they occur in the hand and outlines current treatment methods.





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