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Updated: Nov 8 2025

Ossification of the Posterior Longitudinal Ligament

Images
https://upload.orthobullets.com/topic/2046/images/ct sagittal_moved.jpg
https://upload.orthobullets.com/topic/2046/images/xray lateral.jpg
  • summary
    • Ossification of the posterior longitudinal ligament (OPLL) is an idiopathic cervical spine anomaly that is a common cause of cervical myelopathy in the Asian population
    • Diagnosis is made with lateral radiographs of the cervical spine. CT scan is the study of choice to determine the extent and thickness of the ossification
    • Treatment is observation in patients with minimal symptoms. Surgical decompression followed by stabilization is indicated for patients with myelopathy
  • Epidemiology
    • Demographics
      • Asian (most common, but not limited to)
      • men are more commonly affected than women
    • Anatomic location
      • most common levels are C4-5 and C5-6
      • 95% of ossification is located in the cervical spine
  • Etiology
    • Pathophysiology
      • cause is unclear, but likely multifactorial
      • associated factors include:
        • diabetes
        • obesity
        • high-salt, low-meat diet
        • poor calcium absorption
        • mechanical stress on the posterior longitudinal ligament
  • Presentation
    • Symptoms
      • often asymptomatic
      • myelopathic symptoms
    • Physical exam
      • myelopathy
  • Imaging
    • Radiographs
      • lateral radiograph often shows ossification of PLL
      • used to evaluate the sagittal alignment of cervical spine
    • MRI
      • study of choice to evaluate spinal cord compression
    • CT
      • study of choice to delineate the bony anatomy of the ossified posterior longitudinal ligament
  • Treatment
    • Nonoperative
      • observation
        • indicated only in patients with mild symptoms who are not candidates for surgery
    • Operative
      • direct or indirect surgical decompression, followed by stabilization
        • indications
          • most patients with significant symptoms
  • Techniques
    • Interbody fusion without decompression
      • indications
        • dynamic myelopathy
      • technique
        • the theory behind this technique is that eliminating motion at stenotic levels prevents trauma to the cord
    • Anterior corpectomy with or without OPLL resection
      • indications
        • patients with a kyphotic cervical spine where posterior decompression is not an option
      • technique
        • one method to avoid a dural tear is to perform a corpectomy, and instead of removing the OPLL from the dura, allow it to "float" in the corpectomy site
    • Posterior laminoplasty or laminectomy with fusion
      • indications
        • only effective in patients with a lordotic spine, as it allows the spinal cord to drift away from the anterior compression from the OPLL
        • considered a safer and preferable approach due to the difficulty of resecting the OPLL off the dura from an anterior approach
      • techniques
        • fusion should accompany laminectomy to avoid post-laminectomy kyphosis
      • complications
        • risk of postoperative OPLL growth
  • Complications
    • Recurrence of OPLL
      • reduced with
        • complete resection
        • leaving OPLL to float into a corpectomy site
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Spine | Ossification Posterior Longitudinal Ligament
  • Spine
  • - Ossification of the Posterior Longitudinal Ligament
8:32 min
2/21/2022
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