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It is related to the toughness of the polyethylene liner
3%
102/3386
It is more likely to occur with highly cross-linked polyethylene compared to conventional polyethylene
2%
55/3386
It is caused by macrophage activation by polyethylene particles
93%
3150/3386
It is most frequently caused by infection
1%
22/3386
It occurs more frequently in patients taking immunosuppressive medications.
43/3386
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The radiograph demonstrates polyethylene wear and osteolysis around the femoral component of a total knee replacement. Osteolysis is caused by macrophage activation from polyethylene particles. Ingham et al reviews the pathologic role of macrophages in osteolysis. Answer #1 is incorrect because toughness of the polyethylene is not related to wear rate, but does affect its overall mechanical strength. Answer #2 is incorrect because highly cross-linked polyethylene liners have lower wear rates compared to conventional polyethylene. The listed reference by Huang concludes that there is an increased rate of osteolysis in mobile bearing TKA. This is a contradictory finding as mobile-bearing designs were created to decrease the stress and subsequent wear of the polyethylene
3.8
(21)
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